13 May 2019
At some point in your life, or several times, you suffer pain, and your first choice for relieving this, is to consume analgesics, but, you need to know everything about them?
The two main categories of analgesics commonly used are acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin and drugs known as COX-2 inhibitors and they are available over the counter of pharmacies. Nowadays more than a dozen painkillers have flooded the market. Many are commercially available and can be purchased without a prescription; others, however, can’t be purchased without a prescription.
What is the difference between the two types of drugs?
The NSAIDs relieve pain, reduce fever and inflammation. They can be very helpful to pain from inflammation-related conditions such as arthritis. Acetaminophen relieves pain and fever but does not affect inflammation.
What’s the mystery behind them?
There are indeed things you should know about them. Find out here!
1- Heart pain: Besides aspirin, NSAIDs is safe naproxen for people suffering from heart issues. Also, you can consume aspirin. This helps prevent clots in the bloodstream. NSAIDs do revolutionize the treatment of pain, but as in the case with all drugs, have some drawbacks. Regular use of NSAIDs has been associated with an increased risk of heart disease. Among non-aspirin NSAIDs, naproxen appears to be safe for the heart, however, its consumption should be moderate, for a short period of time and whenever recommended by a doctor.
If you take NSAIDs regularly, never stop taking it abruptly. Stopping suddenly becomes more likely to form blood clots, increasing the chances of having a heart attack or stroke.
2- Kidney pain: NSAIDs, COX-2 including drugs, can create difficulty for the people kidneys issues and, in extreme cases, cause kidney failure. Signs of kidney disease include inexplicable nausea or vomiting, loss of appetite, fatigue, and weakness, changes in urine, persistent itching and other so-called nonspecific symptoms.
The NSAIDs should be used occasionally for a headache or other aches and wisely.
- Stomach pain: The use of NSAIDs is associated with gastrointestinal toxicity from mild to severe. All NSAIDs, including new COX-2 inhibitors, can cause disorder of the stomach from ulcers to gastrointestinal bleeding. These problems tend to arise after prolonged use or when taken in large quantities in a short period of time.
Acetaminophen (paracetamol) is not an anti-inflammatory agent and relieves pain differently than NSAIDs. It is much friendly to the stomach than NSAIDs.
- Blood pressure: Most NSAIDs, including drugs COX-2 tend to raise blood pressure. The effect is stronger and occurs most often to people with hypertension and those people who are taking medication to control it, but there is evidence that these also affect people with normal blood pressure.
5- Adverse reactions: In the case of paracetamol, there’re chances of happening the development of neutropenia and pancytopenia, and in some cases severe nausea, drowsiness, and hemolytic anemia.
Note: This article is published on research base…